Principle Scientist LNP Innovation
- Geleen, Limburg
- Vast
- Voltijds
- Design advanced experimental plans, lead the execution, data evaluation, write and review high quality reports
- Lead multi-disciplinary matrix teams on complex projects in the area of scientific expertise. Lead problem solving and lessons learned activities
- Provide strong scientific, technical and regulatory leadership and for individual scientists and lab technicians on complex projects
- Assess novel technologies on paper and experimentally, also in exchange with external partners
- Perform scale-up of promising technology to support implementation in the LNP manufacturing platform
- Provide solutions to identified risks, issues, problems. Report issues in a timely fashion.
- Act as a deputy of the team manager when needed
- Facilitate improvements to departmental business processes and contribute to the implementation of innovative technologies
- Demonstrate flexibility to support other activities within the department
- Proactive approach to own continuous professional development
- PhD. in Chemistry, Biochemistry, Pharmaceutical Sciences or related field (e.g bioengineering, chemical engineering)
- Experience and strong hands-on power in encapsulation development for biomolecules, with preferred experience with mRNA formulation in lipid nanoparticles
- Experience required in scaling-up of encapsulation and downstream processing by TFF
- Desirable experience in conjugation of targeting moieties to LNP and their characterization
- Expert-level experience & understanding of handling, purification and processing of biomolecules.
- Experience with a wide range of analytical techniques for LNP characterization
- Demonstrated ability to efficiently work in a fast paced and fluid environment, changes in priority and timeline restrictions
Banenrijklimburg