PhD position in RNA Structural Ensemble Dynamics (1.0 FTE)
- Groningen, Groningen
- € 2.901 per maand
- Tijdelijk
- Voltijds
- Develop novel methods (both wet and computational) for the accurate interrogation of RNA 2D and 3D structures in living cells.
- Apply novel as well as state-of-the-art methods to map and functionally characterize RNA structure ensembles under different cellular conditions.
- Explore the therapeutic potential of targeting RNA structure ensembles.
Founded in 1614, the University of Groningen enjoys an international reputation as a dynamic and innovative center of higher education offering high-quality teaching and research. Flexible study programmes and academic career opportunities in a wide variety of disciplines encourage the 33,000 students and researchers alike to develop their own individual talents. As one of the best research universities in Europe, the University of Groningen has joined forces with other top universities and networks worldwide to become a truly global center of knowledge.The Groningen Biomolecular Sciences and Biotechnology Institute (GBB - ), one of the larger institutes of the Faculty of Science and Engineering (FSE), provides an excellent environment for top-notch research in the field of biomolecular sciences. Twelve vibrant research groups with strong roots in biophysics, biochemistry & molecular biology, cell biology, chemistry, computational biology, microbiology or genetics are organized in two focal areas: 'Molecular Mechanisms of Biological Processes' and 'Physiology and Systems Biology'.QualificationsThe ideal candidate must be highly motivated, hard-working, ambitious, creative, and really enthusiastic about RNA. Preferably, we seek candidates who are interested in conducting both wet-lab and in silico research. They will have the following qualifications.Required:
- MSc degree with specialization in molecular biology, biochemistry, bioinformatics/computational biology (or related disciplines).
- Experience with basic molecular biology research techniques (PCR, cloning, western blotting, etc.).
- Excellent command of the English language (both written and spoken).
- Ability to work independently and in a team.
- Prior experience working with RNA and related techniques (RT-PCR, in vitro transcription, northern blotting, etc.).
- Knowledge of UNIX/Linux computing environments and of a programming language (e.g., Perl, Python, Rust, C++, R, etc.).
- A salary of € 2,901 gross per month in the first year to a maximum of € 3,707 gross per month in the final year, based on a fulltime position (1.0 FTE)
- Excluding a 8% holiday allowance and a 8.3% end of the year bonus.
- A temporary position of one year with the option of renewal for another three years. Prolongation of the contract is contingent on sufficient progress in the first year to indicate that a successful completion of the PhD thesis within the contract period is to be expected. A PhD training programme is part of the agreement and the successful candidate will be enrolled in the Graduate School Science and Engineering of the Faculty.
- Cover letter with background and motivation to apply for this position.
- Curriculum vitae, including details of bachelor and master degrees, labwork experience and a publication list, if applicable.
- Detailed (1-2 pages) description of previous research experience, such as the Bachelor/Master research projects.
- Contact details of 2 academic references who can provide information on your suitability for the position.