Senior Research Associate, Bioanalytical Science

Genmab

  • Utrecht
  • Contract
  • Voltijds
  • 1 maand geleden
At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.Does this inspire you and feel like a fit? Then we would love to have you join us!The RoleThe Bioanalytical Science department is responsible for developing fit-for-purpose bioanalytical strategies and methods to quantify drug levels in circulation and assess unwanted immunogenicity. We are experts in the design, development, validation, execution, and interpretation of bioanalytical methods, with a focus on pharmacokinetics/pharmacodynamics (PK/PD), anti-drug antibodies (ADA), neutralizing antibodies (NAb), and soluble biomarkers. We perform bioanalysis for both regulated (GLP, GCP) and non-regulated (e.g., mouse studies, exploratory toxicology, and dose range finding) studies. Our work translates indispensable, high-quality bioanalytical data into conclusive insights that power decisions across all stages of Genmab’s drug development pipeline.As a Senior Research Associate in the Bioanalytical Science team, you will play a pivotal role in accelerating the development of Genmab’s innovative therapeutic formats and compounds. Working closely with the Scientific Lead, you will develop, qualify, and execute immunoassays and LC-MS/MS assays, and take full responsibility for the associated experimental lab work. You will generate, process, and report data with a high level of quality and scientific integrity. In doing so, you will help inform on safety and efficacy during product development and support the registration of new therapeutic products. This role operates in a GLP/GCP-regulated environment, where you will follow relevant guidelines and standard operating procedures to ensure the reliability and compliance of all data generated.Ready to own your experiments, thrive in GLP, and make a real impact for cancer patients?Responsibilities
  • Work together with the Scientific Lead to develop, qualify and execute immunoassays – efficiently and independently organize the execution of development and analysis plans in the laboratory;
  • Ensure compliance to GLP/GCP guidelines and carry out tasks according to standard operating procedures and study-specific plans;
  • Support process improvement/technology innovation projects;
  • Set high quality standards and document results accurately;
  • Act as a mentor to others within the team; set standards; train others in correct execution of methods, processes, procedures and technologies.
Requirements
  • You have a completed HLO education or equivalent;
  • You have 3-5 years of relevant work experience in development and execution of Ligand Binding (ELISA, ECLIA, SIMOA) and LC-MS/MS assays (preferably in an industry setting) for quantification and characterization in biological samples;
  • You have demonstrated experience with regulatory bioanalysis and knowledge of relevant guidance documents as well as GLP/GCP experience;
  • You can work to set guidelines, you document results accurately and are focused on output and results;
  • You are well-organized, can work to tight deadlines, and enjoy alternating between office and laboratory activities;
  • You can communicate plans and results clearly to the team and other parties involved;
  • You are familiar with basic statistical and data analysis software such as Excel, GraphPad Prism, design expert and SoftMax Pro;
  • You are fluent in Dutch and English.
About YouYou are genuinely passionate about our purposeYou bring precision and excellence to all that you doYou believe in our rooted-in-science approach to problem-solvingYou are a generous collaborator who can work in teams with a broad spectrum of backgroundsYou take pride in enabling the best work of others on the teamYou can grapple with the unknown and be innovativeYou have experience working in a fast-growing, dynamic company (or a strong desire to)You work hard and are not afraid to have a little fun while you do so!LocationsGenmab maximizes the efficiency of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are crafted as open, community-based spaces that work to connect employees while being immersed in our powerful laboratories. Whether you’re in one of our office spaces or working remotely, we thrive on connecting with each other to innovate.About GenmabGenmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on and .Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website .Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the contract.

Genmab